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4PY1:
Crystal structure of Tyk2 in complex with compound 15, 6-((2,5-dimethoxyphenyl)thio)-3-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine
PDB ID:
4PY1
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MMDB ID:
122902
PDB Deposition Date:
2014/3/25
Updated in MMDB:
2017/12
Experimental Method:
x-ray diffraction
Resolution:
2.16 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 4PY1: monomeric; determined by author and by software (PISA)
Molecular Components in 4PY1
Label
Count
Molecule
Protein (1 molecule)
A
1
Non-receptor Tyrosine-protein Kinase Tyk2
(Gene symbol:
TYK2
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-[(2,5-dimethoxyphenyl)sulfanyl]-3-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303