4PVX: Crystal structure of human FPPS in complex with [({4-[4-(cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid)

PDB ID: 4PVXDownload
MMDB ID: 128558
PDB Deposition Date: 2014/3/18
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.18  Å
Source Organism:
Similar Structures:
Biological Unit for 4PVX: dimeric; determined by author and by software (PISA)
Molecular Components in 4PVX
Label Count Molecule
Proteins (2 molecules)
2
Farnesyl Pyrophosphate Synthase
(Gene symbol: FDPS)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
6
MAGNESIUM IONMAGNESIUM ION
2
2
[({4-[4-(cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid)[({4-[4-(cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid)
3
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303