4PVO: Crystal Structure of VIM-2 metallo-beta-lactamase in complex with ML302 and ML302F

PDB ID: 4PVODownload
MMDB ID: 124863
PDB Deposition Date: 2014/3/18
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.48  Å
Source Organism:
Similar Structures:
Biological Unit for 4PVO: monomeric; determined by author and by software (PISA)
Molecular Components in 4PVO
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase Class B Vim-2
(Gene symbol: blaVIM-2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
ZINC IONZINC ION
2
1
(2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid(2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid
3
1
N-(4-methylpiperazin-1-yl)-2-[(5Z)-4-oxo-2-thioxo-5-(2,3,6-trichlorobenzylidene)-1,3-thiazolidin-3-yl]acetamideN-(4-methylpiperazin-1-yl)-2-[(5Z)-4-oxo-2-thioxo-5-(2,3,6-trichlorobenzylidene)-1,3-thiazolidin-3-yl]acetamide
4
2
FORMIC ACIDFORMIC ACID
5
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303