4PVG: Crystal structure of protein tyrosine phosphatase Shp2 catalytic domain complex with small molecular compound L88N79

PDB ID: 4PVGDownload
MMDB ID: 128557
PDB Deposition Date: 2014/3/17
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 4PVG: monomeric; determined by author and by software (PISA)
Molecular Components in 4PVG
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Phosphatase Non-receptor Type 11
(Gene symbol: PTPN11)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[3-({4-[(1,3-benzodioxol-5-ylmethyl)amino]-4-oxobutanoyl}amino)phenyl]-6-hydroxy-3-iodo-1-methyl-1H-indole-5-carboxylic acid2-[3-({4-[(1,3-benzodioxol-5-ylmethyl)amino]-4-oxobutanoyl}amino)phenyl]-6-hydroxy-3-iodo-1-methyl-1H-indole-5-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303