4PUW: Human Aldose Reductase complexed with a ligand with an IDD structure (2-[5-fluoro-2-(prop-2-ynylcarbamoyl)phenoxy]acetic acid) at 1.12 A

PDB ID: 4PUWDownload
MMDB ID: 128378
PDB Deposition Date: 2014/3/14
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.12  Å
Source Organism:
Similar Structures:
Biological Unit for 4PUW: monomeric; determined by author and by software (PISA)
Molecular Components in 4PUW
Label Count Molecule
Protein (1 molecule)
1
Aldose Reductase
(Gene symbol: AKR1B1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
[5-fluoro-2-(prop-2-yn-1-ylcarbamoyl)phenoxy]acetic acid (Link to PubChem not yet available)[5-fluoro-2-(prop-2-yn-1-ylcarbamoyl)phenoxy]acetic acid
2
1
CITRIC ACID (Link to PubChem not yet available)CITRIC ACID
3
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (Link to PubChem not yet available)NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303