4PI3: Crystal structure analysis of cruzain bound to vinyl sulfone analog of WRR-483 (WRR-666)

PDB ID: 4PI3Download
MMDB ID: 127796
PDB Deposition Date: 2014/5/8
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.27  Å
Source Organism:
Similar Structures:
Biological Unit for 4PI3: monomeric; determined by author
Molecular Components in 4PI3
Label Count Molecule
Protein (1 molecule)
1
Cruzipain
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[(2S)-5-(carbamimidamidooxy)-1-oxo-1-{[(1E,3S)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl]amino}pentan-2-yl]-4-methylpiperazine-1-carboxamideN-[(2S)-5-(carbamimidamidooxy)-1-oxo-1-{[(1E,3S)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl]amino}pentan-2-yl]-4-methylpiperazine-1-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303