4PH9: The structure of Ibuprofen bound to cyclooxygenase-2

PDB ID: 4PH9Download
MMDB ID: 125048
PDB Deposition Date: 2014/5/5
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.81  Å
Source Organism:
Similar Structures:
Biological Unit for 4PH9: dimeric; determined by author and by software (PISA)
Molecular Components in 4PH9
Label Count Molecule
Proteins (2 molecules)
2
Prostaglandin G/H Synthase 2
(Gene symbol: Ptgs2)
Molecule annotation
Chemicals and Non-standard biopolymers (34 molecules)
1
9
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
alpha-D-mannopyranosealpha-D-mannopyranose
3
2
IBUPROFENIBUPROFEN
4
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
5
3
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
6
4
ACRYLIC ACIDACRYLIC ACID
7
13
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303