4PES: Crystal structure of insulin degrading enzyme complexed with inhibitor tert-butyl [(2S)-2-(2,5-difluorophenyl)-3-(quinolin-3-yl)propyl]carbamate

PDB ID: 4PESDownload
MMDB ID: 130042
PDB Deposition Date: 2014/4/24
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.21  Å
Source Organism:
Similar Structures:
Biological Unit for 4PES: dimeric; determined by author and by software (PISA)
Molecular Components in 4PES
Label Count Molecule
Proteins (2 molecules)
1
Insulin-degrading Enzyme
(Gene symbol: IDE)
Molecule annotation
1
Ala-ala-ala
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
tert-butyl [(2S)-2-(2,5-difluorophenyl)-3-(quinolin-3-yl)propyl]carbamatetert-butyl [(2S)-2-(2,5-difluorophenyl)-3-(quinolin-3-yl)propyl]carbamate
2
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303