4P8P: Crystal structure of M. tuberculosis DprE1 in complex with the non-covalent inhibitor QN127

PDB ID: 4P8PDownload
MMDB ID: 125412
PDB Deposition Date: 2014/3/31
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 4P8P: monomeric; determined by software (PISA)
Molecular Components in 4P8P
Label Count Molecule
Protein (1 molecule)
1
Probable Decaprenylphosphoryl-beta-d-ribose Oxidase
(Gene symbol: dprE1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
2
1
3-[(4-chlorobenzyl)amino]-6-(trifluoromethyl)quinoxaline-2-carboxylic acid3-[(4-chlorobenzyl)amino]-6-(trifluoromethyl)quinoxaline-2-carboxylic acid
3
1
(2R)-2-{[(2R)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propan-1-ol(2R)-2-{[(2R)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propan-1-ol
4
1
IMIDAZOLEIMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303