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4P45:
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor JRB-4-73
PDB ID:
4P45
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MMDB ID:
129402
PDB Deposition Date:
2014/3/11
Updated in MMDB:
2024/12
Experimental Method:
x-ray diffraction
Resolution:
1.87 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4P45: dimeric; determined by software (PISA)
Molecular Components in 4P45
Label
Count
Molecule
Proteins (2 molecules)
A
A_1
2
Glutamate Carboxypeptidase 2
(Gene symbol:
FOLH1
)
Chemicals and Non-standard biopolymers (35 molecules)
1
18
2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
alpha-L-fucopyranose
3
3
beta-D-mannopyranose
4
4
ZINC ION
5
2
CALCIUM ION
6
2
CHLORIDE ION
7
2
N-(4-fluorobenzoyl)-L-valyl-O-[(S)-{[(1S)-1,3-dicarboxypropyl]amino}(hydroxy)phosphoryl]-L-serine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303