4P44: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor JRB-4-81

PDB ID: 4P44Download
MMDB ID: 129401
PDB Deposition Date: 2014/3/11
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 4P44: monomeric; determined by software (PISA)
Molecular Components in 4P44
Label Count Molecule
Protein (1 molecule)
1
Glutamate Carboxypeptidase 2
(Gene symbol: FOLH1)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
11
N-ACETYL-D-GLUCOSAMINEN-ACETYL-D-GLUCOSAMINE
2
1
BETA-D-MANNOSEBETA-D-MANNOSE
3
1
ALPHA-D-MANNOSEALPHA-D-MANNOSE
4
2
ZINC IONZINC ION
5
1
CALCIUM IONCALCIUM ION
6
1
CHLORIDE IONCHLORIDE ION
7
1
N-(4-fluorobenzoyl)-L-alloisoleucyl-O-[(S)-{[(1S)-1,3-dicarboxypropyl]amino}(hydroxy)phosphoryl]-L-serineN-(4-fluorobenzoyl)-L-alloisoleucyl-O-[(S)-{[(1S)-1,3-dicarboxypropyl]amino}(hydroxy)phosphoryl]-L-serine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303