4OTJ: The Complex Of Murine Cyclooxygenase-2 With A Conjugate Of Indomefathin And Podophyllotoxin, N-{(succinylpodophyllotoxinyl)but- 4-yl}-2-{1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indol-3- Yl}acetamide

PDB ID: 4OTJDownload
MMDB ID: 128355
PDB Deposition Date: 2014/2/13
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 2.11  Å
Source Organism:
Similar Structures:
Biological Unit for 4OTJ: dimeric; determined by author and by software (PISA)
Molecular Components in 4OTJ
Label Count Molecule
Proteins (2 molecules)
2
Prostaglandin G/H Synthase 2
(Gene symbol: Ptgs2)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
8
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
2
2
Protoporphyrin Ix Containing FeProtoporphyrin Ix Containing Fe
3
2
(5s,5as,8as,9s)-8-Oxo-9-(3,4,5-Trimethoxyphenyl)-5,5a,6,8,8a,9-Hexahydrofuro[3',4':6,7]naphtho[2,3-D][1,3]dioxol-5-Yl 4-{[4-({[1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-1h-Indol-3-Yl]acetyl}amino)butyl]amino}-4-Oxobutanoate(5s,5as,8as,9s)-8-Oxo-9-(3,4,5-Trimethoxyphenyl)-5,5a,6,8,8a,9-Hexahydrofuro[3',4':6,7]naphtho[2,3-D][1,3]dioxol-5-Yl 4-{[4-({[1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-1h-Indol-3-Yl]acetyl}amino)butyl]amino}-4-Oxobutanoate
4
1
B-OctylglucosideB-Octylglucoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303