NCBI
National Center for
Biotechnology Information
Search
4OR7:
Klebsiella pneumoniae dihydrofolate reductase complexed with NADPH and 6-ethyl-5-{3-[3-(pyrimidin-5-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine
PDB ID:
4OR7
Download
MMDB ID:
125202
PDB Deposition Date:
2014/2/11
Updated in MMDB:
2014/12
Experimental Method:
x-ray diffraction
Resolution:
1.76 Å
Source Organism:
Klebsiella pneumoniae CG43
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4OR7: monomeric; determined by author and by software (PISA)
Molecular Components in 4OR7
Label
Count
Molecule
Protein (1 molecule)
A
1
Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
6-ethyl-5-{3-[3-(pyrimidin-5-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303