4OPB: AA13 Lytic polysaccharide monooxygenase from Aspergillus oryzae

Citation:
Abstract
Lytic polysaccharide monooxygenases (LPMOs) are recently discovered enzymes that oxidatively deconstruct polysaccharides. LPMOs are fundamental in the effective utilization of these substrates by bacteria and fungi; moreover, the enzymes have significant industrial importance. We report here the activity, spectroscopy and three-dimensional structure of a starch-active LPMO, a representative of the new CAZy AA13 family. We demonstrate that these enzymes generate aldonic acid-terminated malto-oligosaccharides from retrograded starch and boost significantly the conversion of this recalcitrant substrate to maltose by beta-amylase. The detailed structure of the enzyme's active site yields insights into the mechanism of action of this important class of enzymes.
PDB ID: 4OPBDownload
MMDB ID: 156743
PDB Deposition Date: 2014/2/5
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4OPB: monomeric; determined by author and by software (PISA)
Molecular Components in 4OPB
Label Count Molecule
Protein (1 molecule)
1
Predicted Protein
Molecule annotation
Chemicals (17 molecules)
1
1
2
1
3
4
4
2
5
7
6
2
* Click molecule labels to explore molecular sequence information.

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