4OME: X-ray Structure Of Human Glutamate Carboxypeptidase Ii In Complex With Dccbl, A Urea Based Inhibitor With Distal Carborane Moiety

PDB ID: 4OMEDownload
MMDB ID: 127079
PDB Deposition Date: 2014/1/27
Updated in MMDB: 2015/02
Experimental Method:
x-ray diffraction
Resolution: 1.79  Å
Source Organism:
Similar Structures:
Biological Unit for 4OME: dimeric; determined by author and by software (PISA)
Molecular Components in 4OME
Label Count Molecule
Proteins (2 molecules)
2
Glutamate Carboxypeptidase 2
(Gene symbol: FOLH1)
Molecule annotation
Chemicals and Non-standard biopolymers (32 molecules)
1
20
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
2
2
Beta-D-MannoseBeta-D-Mannose
3
4
Zinc IonZinc Ion
4
2
Calcium IonCalcium Ion
5
2
Chloride IonChloride Ion
6
2
(S)-2-(3-((S)-1-Carboxy-5-(1,2-Dicarba-Closo-Dodecarboranylamido) Pentyl)ureido)pentanedioic Acid(S)-2-(3-((S)-1-Carboxy-5-(1,2-Dicarba-Closo-Dodecarboranylamido) Pentyl)ureido)pentanedioic Acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303