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4OFH:
Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis
PDB ID:
4OFH
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MMDB ID:
128712
PDB Deposition Date:
2014/1/14
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.22 Å
Source Organism:
synthetic construct
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Taxonomy
Molecule
synthetic construct
C, D
Homo sapiens
A
Similar Structures:
VAST+
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Biological Unit for 4OFH: trimeric; determined by author and by software (PISA)
Molecular Components in 4OFH
Label
Count
Molecule
Protein (1 molecule)
A
1
Methyl-cpg-binding Domain Protein 4
Nucleotides(2 molecules)
C
1
12-mer DNA(t)
D
1
12-mer DNA(o6meg)
Chemical and Non-standard biopolymers (1 molecule)
1
1
MAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303