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4OBC:
Crystal structure of HCV polymerase NS5b genotype 2a JFH-1 isolate with the S15G, C223H, V321I resistance mutations against the guanosine analog GS-0938 (PSI-3529238)
PDB ID:
4OBC
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MMDB ID:
123023
PDB Deposition Date:
2014/1/7
Updated in MMDB:
2017/12
Experimental Method:
x-ray diffraction
Resolution:
2.5 Å
Source Organism:
Hepatitis C virus JFH-1
Similar Structures:
VAST+
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Biological Unit for 4OBC: monomeric; determined by author and by software (PISA)
Molecular Components in 4OBC
Label
Count
Molecule
Protein (1 molecule)
A
1
RNA-directed RNA Polymerase
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID
2
2
GLYCEROL
3
1
1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE
4
1
CHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303