4O17: Structural Basis For Resistance To Diverse Classes Of Nampt Inhibitors

PDB ID: 4O17Download
MMDB ID: 124039
PDB Deposition Date: 2013/12/15
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 1.82  Å
Source Organism:
Similar Structures:
Biological Unit for 4O17: dimeric; determined by author and by software (PISA)
Molecular Components in 4O17
Label Count Molecule
Proteins (2 molecules)
2
Nicotinamide Phosphoribosyltransferase
(Gene symbol: NAMPT)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
Phosphate IonPhosphate Ion
2
8
1,2-Ethanediol1,2-Ethanediol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303