4O13: The Crystal Structure Of Nampt In Complex With Gne-618

PDB ID: 4O13Download
MMDB ID: 124035
PDB Deposition Date: 2013/12/15
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 4O13: dimeric; determined by author and by software (PISA)
Molecular Components in 4O13
Label Count Molecule
Proteins (2 molecules)
2
Nicotinamide Phosphoribosyltransferase
(Gene symbol: NAMPT)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
N-(4-{[3-(Trifluoromethyl)phenyl]sulfonyl}benzyl)-2h-Pyrazolo[3,4-B]pyridine-5-CarboxamideN-(4-{[3-(Trifluoromethyl)phenyl]sulfonyl}benzyl)-2h-Pyrazolo[3,4-B]pyridine-5-Carboxamide
2
4
Phosphate IonPhosphate Ion
3
8
1,2-Ethanediol1,2-Ethanediol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303