4NXO: Crystal Structure of Insulin Degrading Enzyme in complex with BDM44768

PDB ID: 4NXODownload
MMDB ID: 133418
PDB Deposition Date: 2013/12/9
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 2.73  Å
Source Organism:
Similar Structures:
Biological Unit for 4NXO: monomeric; determined by author and by software (PISA)
Molecular Components in 4NXO
Label Count Molecule
Protein (1 molecule)
1
Insulin-degrading Enzyme
(Gene symbol: IDE)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
ZINC IONZINC ION
2
1
4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)benzamide4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)benzamide
3
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
4
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303