4NHC: Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41

PDB ID: 4NHCDownload
MMDB ID: 125183
PDB Deposition Date: 2013/11/4
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.912  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4NHC: trimeric; determined by author and by software (PISA)
Molecular Components in 4NHC
Label Count Molecule
Proteins (3 molecules)
1
FAB Light Chain
Molecule annotation
1
FAB Heavy Chain
Molecule annotation
1
Modified Fragment of HIV Glycoprotein (Gp41)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
trifluoroacetic acidtrifluoroacetic acid
2
1
PHOSPHATE IONPHOSPHATE ION
3
1
Molecule information is not available.
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303