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4MQA:
Human beta-tryptase co-crystal structure with {(1,1,3,3-tetramethyldisiloxane-1,3-diyl)bis[5-(methylsulfanyl)benzene-3,1-diyl]}bis({4-[3-(aminomethyl)phenyl]piperidin-1-yl}methanone)
PDB ID:
4MQA
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MMDB ID:
127821
PDB Deposition Date:
2013/9/16
Updated in MMDB:
2024/10
Experimental Method:
x-ray diffraction
Resolution:
2.25 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 4MQA: tetrameric; determined by author and by software (PISA)
Molecular Components in 4MQA
Label
Count
Molecule
Proteins (4 molecules)
A
B
A_1
B_1
4
Tryptase Alpha/beta-1
(Gene symbol:
TPSAB1
)
Chemicals and Non-standard biopolymers (14 molecules)
1
10
SULFATE ION
2
2
TETRAETHYLENE GLYCOL
3
2
{(1,1,3,3-tetramethyldisiloxane-1,3-diyl)bis[5-(methylsulfanyl)benzene-3,1-diyl]}bis({4-[3-(aminomethyl)phenyl]piperidin-1-yl}methanone)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303