4MPV: Human beta-tryptase co-crystal structure with (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide

PDB ID: 4MPVDownload
MMDB ID: 127818
PDB Deposition Date: 2013/9/13
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 2.305  Å
Source Organism:
Similar Structures:
Biological Unit for 4MPV: tetrameric; determined by author and by software (PISA)
Molecular Components in 4MPV
Label Count Molecule
Proteins (4 molecules)
4
Tryptase Alpha/beta-1
(Gene symbol: TPSAB1)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
2
(2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide(2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide
2
8
SULFATE IONSULFATE ION
3
4
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
4
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303