4MPU: Human beta-tryptase co-crystal structure with (6S,8R)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-8-hydroxy-6-(1-hydroxycyclobutyl)-5,7-dioxaspiro[3.4]octane-6,8-dicarboxamide

PDB ID: 4MPUDownload
MMDB ID: 127817
PDB Deposition Date: 2013/9/13
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 1.649  Å
Source Organism:
Similar Structures:
Biological Unit for 4MPU: tetrameric; determined by author and by software (PISA)
Molecular Components in 4MPU
Label Count Molecule
Proteins (4 molecules)
4
Tryptase Alpha/beta-1
(Gene symbol: TPSAB1)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
4
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
2
8
SULFATE IONSULFATE ION
3
4
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
4
2
(6S,8R)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-8-hydroxy-6-(1-hydroxycyclobutyl)-5,7-dioxaspiro[3.4]octane-6,8-dicarboxamide(6S,8R)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-8-hydroxy-6-(1-hydroxycyclobutyl)-5,7-dioxaspiro[3.4]octane-6,8-dicarboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303