4M2X: Mycobacterium Tuberculosis Dihydrofolate Reductase Complexed With Trimetrexate (tmq)

PDB ID: 4M2XDownload
MMDB ID: 124630
PDB Deposition Date: 2013/8/5
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 2.26  Å
Source Organism:
Similar Structures:
Biological Unit for 4M2X: monomeric; determined by author and by software (PISA)
Molecular Components in 4M2X
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
Nadph Dihydro-Nicotinamide-Adenine-Dinucleotide PhosphateNadph Dihydro-Nicotinamide-Adenine-Dinucleotide Phosphate
2
1
TrimetrexateTrimetrexate
3
7
Acetate IonAcetate Ion
4
1
Phosphate IonPhosphate Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303