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4M2X:
Mycobacterium Tuberculosis Dihydrofolate Reductase Complexed With Trimetrexate (tmq)
PDB ID:
4M2X
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MMDB ID:
124630
PDB Deposition Date:
2013/8/5
Updated in MMDB:
2014/11
Experimental Method:
x-ray diffraction
Resolution:
2.26 Å
Source Organism:
Mycobacterium tuberculosis
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4M2X: monomeric; determined by author and by software (PISA)
Molecular Components in 4M2X
Label
Count
Molecule
Protein (1 molecule)
A
1
Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (10 molecules)
1
1
Nadph Dihydro-Nicotinamide-Adenine-Dinucleotide Phosphate
2
1
Trimetrexate
3
7
Acetate Ion
4
1
Phosphate Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303