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4KPE:
Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate
PDB ID:
4KPE
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MMDB ID:
125006
PDB Deposition Date:
2013/5/13
Updated in MMDB:
2014/11
Experimental Method:
x-ray diffraction
Resolution:
3.43 Å
Source Organism:
Streptococcus pneumoniae TIGR4
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Taxonomy
Molecule
Streptococcus pneumoniae TIGR4
A, B, C, D
synthetic construct
E, F, G, H
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4KPE: octameric; determined by author
Molecular Components in 4KPE
Label
Count
Molecule
Proteins (4 molecules)
A
B
2
DNA Topoisomerase 4 Subunit a
C
D
2
DNA Topoisomerase 4 Subunit B
Nucleotides(4 molecules)
E
1
E-site Dna1
F
1
E-site Dna2
G
1
E-site Dna3
H
1
E-site Dna4
Chemicals and Non-standard biopolymers (8 molecules)
1
6
MAGNESIUM ION
2
2
(7aR,8R)-8-amino-4-cyclopropyl-12-fluoro-1-oxo-4,7,7a,8,9,10-hexahydro-1H-pyrrolo[1',2':1,7]azepino[2,3-h]quinoline-2-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303