4KLZ: Inhibition of Small GTPases by Stabilization of the GDP Complex, a Novel Approach applied to Rit1, a Target for Rheumatoid Arthritis

PDB ID: 4KLZDownload
MMDB ID: 123177
PDB Deposition Date: 2013/5/7
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4KLZ: monomeric; determined by author and by software (PISA)
Molecular Components in 4KLZ
Label Count Molecule
Protein (1 molecule)
1
Gtp-binding Protein Rit1
(Gene symbol: RIT1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
GUANOSINE-5'-DIPHOSPHATE (Link to PubChem not yet available)GUANOSINE-5'-DIPHOSPHATE
2
1
MAGNESIUM ION (Link to PubChem not yet available)MAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303