4JA1: Structure Of Mmp3 Complexed With A Platinum-based Inhibitor

Citation:
Abstract
An X-ray investigation has been performed with the aim of characterizing the binding sites of a platinum-based inhibitor (K[PtCl3(DMSO)]) of matrix metalloproteinase-3 (stromelysin-1). The platinum complex targets His224 in the S1' specificity loop, representing the first step in the selective inhibition process (PDB ID code ).
PDB ID: 4JA1Download
MMDB ID: 108020
PDB Deposition Date: 2013/2/18
Updated in MMDB: 2013/06
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 4JA1: monomeric; determined by author and by software (PISA)
Molecular Components in 4JA1
Label Count Molecule
Protein (1 molecule)
1
Stromelysin-1(Gene symbol: MMP3)
Molecule annotation
Chemicals (7 molecules)
1
2
2
3
3
1
4
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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