4IVD: JAK1 kinase (JH1 domain) in complex with compound 34

PDB ID: 4IVDDownload
MMDB ID: 110287
PDB Deposition Date: 2013/1/22
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.93  Å
Source Organism:
Similar Structures:
Biological Unit for 4IVD: monomeric; determined by author and by software (PISA)
Molecular Components in 4IVD
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak1
(Gene symbol: JAK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-(trans-4-{2-[(1R)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl}cyclohexyl)propanenitrile3-(trans-4-{2-[(1R)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl}cyclohexyl)propanenitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303