4FO6: Crystal structure of the pre-catalytic ternary complex of polymerase lambda with a dATP analog opposite a templating T and an rCMP at the primer terminus

PDB ID: 4FO6Download
MMDB ID: 101262
PDB Deposition Date: 2012/6/20
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.007  Å
Source Organism:
unidentified▼
Similar Structures:
Biological Unit for 4FO6: hexameric; determined by author
Molecular Components in 4FO6
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase Lambda
Molecule annotation
Nucleotides(4 molecules)
1
5'-d(*cp*gp*gp*cp*tp*gp*tp*ap*cp*tp*g)-3'
Molecule annotation
1
5'-d(p*gp*cp*cp*g)-3'
Molecule annotation
1
5'-d(p*tp*ap*cp*tp*g)-3'
Molecule annotation
1
5'-d(p*cp*ap*gp*tp*a)-3'
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
P
1
5'-D(*CP*AP*GP*TP*AP)-R(P*C)-3'
1
1
MAGNESIUM IONMAGNESIUM ION
2
2
SODIUM IONSODIUM ION
3
1
CHLORIDE IONCHLORIDE ION
4
1
MANGANESE (II) IONMANGANESE (II) ION
5
1
2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303