4FEU: Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor anthrapyrazolone SP600125

PDB ID: 4FEUDownload
MMDB ID: 100768
PDB Deposition Date: 2012/5/30
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.37  Å
Source Organism:
Similar Structures:
Biological Unit for 4FEU: monomeric; determined by author and by software (PISA)
Molecular Components in 4FEU
Label Count Molecule
Protein (1 molecule)
1
Aminoglycoside 3'-phosphotransferase Apha1-iab
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
KANAMYCIN AKANAMYCIN A
2
1
2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE
3
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303