4F9Y: Human P38 alpha MAPK In Complex With a Novel and Selective Small Molecule Inhibitor

PDB ID: 4F9YDownload
MMDB ID: 256639
PDB Deposition Date: 2012/5/21
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 4F9Y: monomeric; determined by author and by software (PISA)
Molecular Components in 4F9Y
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 14
(Gene symbol: MAPK14)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE
2
1
N,N-dimethyl-6-(naphthalen-1-yl)-5-(pyridin-4-yl)pyridazin-3-amineN,N-dimethyl-6-(naphthalen-1-yl)-5-(pyridin-4-yl)pyridazin-3-amine
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303