4F8H: X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel

PDB ID: 4F8HDownload
MMDB ID: 102465
PDB Deposition Date: 2012/5/17
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.99  Å
Source Organism:
Similar Structures:
Biological Unit for 4F8H: pentameric; determined by author and by software (PISA)
Molecular Components in 4F8H
Label Count Molecule
Proteins (5 molecules)
5
Proton-gated Ion Channel
(Gene symbol: glr4197)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
5
(R)-ketamine(R)-ketamine
2
6
tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosidetetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside
3
10
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303