4EOS: Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor RO3306

PDB ID: 4EOSDownload
MMDB ID: 254413
PDB Deposition Date: 2012/4/14
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.57  Å
Source Organism:
Similar Structures:
Biological Unit for 4EOS: dimeric; determined by author and by software (PISA)
Molecular Components in 4EOS
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin-a2
(Gene symbol: CCNA2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one(5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303