4ELT: Snapshot of the Large Fragment of DNA Polymerase I From Thermus Aquaticus Processing Modified Pyrimidines

Citation:
Abstract
Modified nucleotides play a paramount role in many cutting-edge biomolecular techniques. The present structural study highlights the plasticity and flexibility of the active site of a DNA polymerase while incorporating non-polar "Click-able" nucleotide analogs and emphasizes new insights into rational design guidelines for modified nucleotides.
PDB ID: 4ELTDownload
MMDB ID: 108636
PDB Deposition Date: 2012/4/11
Updated in MMDB: 2013/03
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
synthetic construct
Similar Structures:
Biological Unit for 4ELT: trimeric; determined by author and by software (PISA)
Molecular Components in 4ELT
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase I, Thermostable
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*gp*ap*cp*cp*ap*cp*gp*gp*cp*gp*cp*(doc))-3')
Molecule annotation
1
DNA (5'-d(*ap*ap*ap*ap*gp*gp*cp*gp*cp*cp*gp*tp*gp*gp*tp*c)- 3')
Molecule annotation
Chemicals (17 molecules)
1
1
2
3
3
9
4
3
5
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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