4EJN: Crystal structure of autoinhibited form of AKT1 in complex with N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide

PDB ID: 4EJNDownload
MMDB ID: 99946
PDB Deposition Date: 2012/4/6
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.19  Å
Source Organism:
Similar Structures:
Biological Unit for 4EJN: monomeric; determined by author and by software (PISA)
Molecular Components in 4EJN
Label Count Molecule
Protein (1 molecule)
1
Rac-alpha Serine/threonine-protein Kinase
(Gene symbol: AKT1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-(4-{5-[3-(acetylamino)phenyl]-2-(2-aminopyridin-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl}benzyl)-3-fluorobenzamideN-(4-{5-[3-(acetylamino)phenyl]-2-(2-aminopyridin-3-yl)-3H-imidazo[4,5-b]pyridin-3-yl}benzyl)-3-fluorobenzamide
2
1
2-BUTANOL2-BUTANOL
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303