4EBW: Structure Of Focal Adhesion Kinase Catalytic Domain In Complex With Novel Allosteric Inhibitor

PDB ID: 4EBWDownload
MMDB ID: 101479
PDB Deposition Date: 2012/3/25
Updated in MMDB: 2012/08
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 4EBW: monomeric; determined by author and by software (PISA)
Molecular Components in 4EBW
Label Count Molecule
Protein (1 molecule)
1
Focal Adhesion Kinase 1
(Gene symbol: PTK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-Ethyl-8-(4-Ethylphenyl)-5-Methyl-1,5-Dihydropyrazolo[4,3-C][2,1]benzothiazine 4,4-Dioxide1-Ethyl-8-(4-Ethylphenyl)-5-Methyl-1,5-Dihydropyrazolo[4,3-C][2,1]benzothiazine 4,4-Dioxide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303