4EB4: Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex

PDB ID: 4EB4Download
MMDB ID: 99262
PDB Deposition Date: 2012/3/23
Updated in MMDB: 2012/10
Experimental Method:
x-ray diffraction
Resolution: 1.74  Å
Source Organism:
Similar Structures:
Biological Unit for 4EB4: dimeric; determined by author and by software (PISA)
Molecular Components in 4EB4
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: Tyms)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
2
2
TOMUDEXTOMUDEX
3
1
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
4
7
GLYCEROLGLYCEROL
5
1
SULFATE IONSULFATE ION
6
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303