4EA0: Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651

PDB ID: 4EA0Download
MMDB ID: 99099
PDB Deposition Date: 2012/3/21
Updated in MMDB: 2012/05
Experimental Method:
x-ray diffraction
Resolution: 2.12  Å
Source Organism:
Similar Structures:
Biological Unit for 4EA0: monomeric; determined by author and by software (PISA)
Molecular Components in 4EA0
Label Count Molecule
Protein (1 molecule)
1
Dehydrosqualene Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
3
MAGNESIUM IONMAGNESIUM ION
2
1
PYROPHOSPHATE 2-PYROPHOSPHATE 2-
3
1
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
4
1
(3R)-3-biphenyl-4-yl-1-azabicyclo[2.2.2]octan-3-ol(3R)-3-biphenyl-4-yl-1-azabicyclo[2.2.2]octan-3-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303