4E7R: Thrombin in complex with 3-amidinophenylalanine inhibitor

PDB ID: 4E7RDownload
MMDB ID: 100721
PDB Deposition Date: 2012/3/19
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 4E7R: trimeric; determined by author and by software (PISA)
Molecular Components in 4E7R
Label Count Molecule
Proteins (3 molecules)
1
Thrombin Light Chain
Molecule annotation
1
Thrombin Heavy Chain
Molecule annotation
1
Hirudin Variant-2
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
3-[(2S)-3-[4-(2-aminoethyl)piperidin-1-yl]-2-{[(2',4'-dichlorobiphenyl-3-yl)sulfonyl]amino}-3-oxopropyl]benzenecarboximidamide3-[(2S)-3-[4-(2-aminoethyl)piperidin-1-yl]-2-{[(2',4'-dichlorobiphenyl-3-yl)sulfonyl]amino}-3-oxopropyl]benzenecarboximidamide
3
2
SODIUM IONSODIUM ION
4
1
PHOSPHATE IONPHOSPHATE ION
5
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303