4E6Q: JAK2 kinase (JH1 domain) triple mutant in complex with compound 12

PDB ID: 4E6QDownload
MMDB ID: 100145
PDB Deposition Date: 2012/3/15
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.948  Å
Source Organism:
Similar Structures:
Biological Unit for 4E6Q: monomeric; determined by author and by software (PISA)
Molecular Components in 4E6Q
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak2
(Gene symbol: JAK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-(1-benzylpiperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine1-(1-benzylpiperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303