4E47: SET7/9 in complex with inhibitor (R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6- sulfonamide and S-adenosylmethionine

PDB ID: 4E47Download
MMDB ID: 98422
PDB Deposition Date: 2012/3/12
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4E47: monomeric; determined by author
Molecular Components in 4E47
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase Setd7
(Gene symbol: SETD7)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
2
1
(R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide(R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide
3
1
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303