4DTK: Novel and selective pan-PIM kinase inhibitor

PDB ID: 4DTKDownload
MMDB ID: 101213
PDB Deposition Date: 2012/2/21
Updated in MMDB: 2012/08
Experimental Method:
x-ray diffraction
Resolution: 1.86  Å
Source Organism:
Similar Structures:
Biological Unit for 4DTK: monomeric; determined by author and by software (PISA)
Molecular Components in 4DTK
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Pim-1
(Gene symbol: PIM1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
(5Z)-5-{2-[(3R)-3-aminopiperidin-1-yl]-3-(propan-2-yloxy)benzylidene}-1,3-thiazolidine-2,4-dione(5Z)-5-{2-[(3R)-3-aminopiperidin-1-yl]-3-(propan-2-yloxy)benzylidene}-1,3-thiazolidine-2,4-dione
3
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303