4DTG: Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model

PDB ID: 4DTGDownload
MMDB ID: 100523
PDB Deposition Date: 2012/2/21
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 4DTG: trimeric; determined by author
Molecular Components in 4DTG
Label Count Molecule
Proteins (3 molecules)
1
Humanized Recombinant FAB Fragment, FAB 2021, of a Murine Antibody, Light Chain
Molecule annotation
1
Humanized Recombinant FAB Fragment, FAB 2021, of a Murine Antibody, Heavy Chain
Molecule annotation
1
Tissue Factor Pathway Inhibitor
(Gene symbol: TFPI)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
10
GLYCEROLGLYCEROL
2
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
3
3
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303