4DQB: Crystal Structure of wild-type HIV-1 Protease in Complex with DRV

PDB ID: 4DQBDownload
MMDB ID: 97854
PDB Deposition Date: 2012/2/15
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4DQB: dimeric; determined by author and by software (PISA)
Molecular Components in 4DQB
Label Count Molecule
Proteins (2 molecules)
2
Aspartyl Protease
(Gene symbol: gag-pol)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
3
1
PHOSPHATE IONPHOSPHATE ION
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303