4DL4: Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1)

PDB ID: 4DL4Download
MMDB ID: 99420
PDB Deposition Date: 2012/2/5
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4DL4: trimeric; determined by author and by software (PISA)
Molecular Components in 4DL4
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase ETA
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(p*gp*gp*cp*tp*cp*ap*cp*ap*cp*t)-3')
Molecule annotation
1
DNA (5'-d(*tp*ap*gp*tp*gp*tp*gp*ap*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
1
GLYCEROLGLYCEROL
3
1
CisplatinCisplatin
4
1
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303