4DFU: Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin

PDB ID: 4DFUDownload
MMDB ID: 97162
PDB Deposition Date: 2012/1/24
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 4DFU: monomeric; determined by author
Molecular Components in 4DFU
Label Count Molecule
Protein (1 molecule)
1
Aph(2")-id
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
KANAMYCIN AKANAMYCIN A
2
2
3,5,7,3',4'-PENTAHYDROXYFLAVONE3,5,7,3',4'-PENTAHYDROXYFLAVONE
3
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303