4DFR: CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE

PDB ID: 4DFRDownload
MMDB ID: 3154
PDB Deposition Date: 1982/6/25
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 4DFR: dimeric; determined by author
Molecular Components in 4DFR
Label Count Molecule
Proteins (2 molecules)
2
Dihydrofolate Reductase
(Gene symbol: folA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
2
METHOTREXATEMETHOTREXATE
3
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303