4D7G: Human FXIa in complex with small molecule inhibitors

PDB ID: 4D7GDownload
MMDB ID: 135610
PDB Deposition Date: 2014/11/24
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.33  Å
Source Organism:
Similar Structures:
Biological Unit for 4D7G: monomeric; determined by author
Molecular Components in 4D7G
Label Count Molecule
Protein (1 molecule)
1
Coagulation Factor XIA
(Gene symbol: F11)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
6
GLYCEROLGLYCEROL
2
1
N-[(1S)-1-benzyl-2-(3-guanidinopropylamino)-2-oxo-ethyl]-4-hydroxy-2-oxo-1H-quinoline-6-carboxamideN-[(1S)-1-benzyl-2-(3-guanidinopropylamino)-2-oxo-ethyl]-4-hydroxy-2-oxo-1H-quinoline-6-carboxamide
3
5
SULFATE IONSULFATE ION
4
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303