4D33: Structure of bovine endothelial nitric oxide synthase heme domain in complex with (N1-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)-N2-(3- fluorophenethyl)ethane-1,2-diamine

PDB ID: 4D33Download
MMDB ID: 127566
PDB Deposition Date: 2014/10/20
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.087  Å
Source Organism:
Similar Structures:
Biological Unit for 4D33: dimeric; determined by software (PISA)
Molecular Components in 4D33
Label Count Molecule
Proteins (2 molecules)
2
Nitric Oxide Synthase, Endothelial
(Gene symbol: NOS3)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
5,6,7,8-TETRAHYDROBIOPTERIN5,6,7,8-TETRAHYDROBIOPTERIN
3
2
N-[2-(3-fluorophenyl)ethyl]-N'-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]ethane-1,2-diamineN-[2-(3-fluorophenyl)ethyl]-N'-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]ethane-1,2-diamine
4
2
ACETATE IONACETATE ION
5
2
D-MANNITOLD-MANNITOL
6
2
GLYCEROLGLYCEROL
7
1
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
8
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303